Kerala University has achieved a groundbreaking milestone in diabetic wound care with the patenting of a revolutionary hydrogel dressing.

The innovation behind the hydrogel Developed by the Department of Biochemistry, this biocompatible hydrogel marks a significant advancement in regenerative medicine, offering new hope for effective wound care.

Titled ‘Synthesis of Ferulic Acid Incorporated Alginate Dialdehyde Gelatin Hydrogel Film’, this invention was created by research scholar Fathima Rumaisa, under the guidance of Professor Mini S, both of the Department of Biochemistry.

Diabetic patients often struggle with chronic wounds that are difficult to heal. This hydrogel aims to speed up healing, potentially changing the future of wound care for millions worldwide.

Key healing ingredients The hydrogel incorporates two powerful components: Ferulic acid: A natural compound found in whole grains, blackberries, and spinach, it’s known for its healing, anti-inflammatory, and anti-diabetic properties. It stimulates the growth of new blood vessels, thereby expediting the healing of diabetic wounds.

 L-Proline: An amino acid that supports collagen production, which is essential for faster wound healing.

Colour-changing technology A unique feature of this hydrogel is its ability to change colour to bluish-green when a wound becomes infected. This visual indicator ensures timely treatment, potentially preventing complications.

The hydrogel has functionality at its core. The design closely mimics the properties of human skin, making it more effective than existing alternatives in promoting wound healing.

Pre-clinical studies on rats have shown positive outcomes, and the team is now preparing for human clinical trials to further evaluate the hydrogel’s potential.

The path forward The patent has been granted for a period of 20 years from 3 February, 2024, the date of filing of the application.